Open 24 hours, 7 days a week! What's happening. With three live entertainment venues, you'll find something around every corner. These casinos and gaming sites are owned by 14 New Mexico. Seadust Cancun Family Resort · 6, reviews. The Pyramid Cancun · 4, reviews. No Smoking Facility. Unwind. Learn More. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. . Indulge. Win. The Travel center includes a casino area with 45 slot machines. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Must be 21+. Our New Mexico casino is open 24/7 daily. A warm and friendly environment with slot machines at the Main Casino. Sky City Casino is open 24 hours daily. #2 Best Value of 24 Mexico. #1 Best Value of 24 Mexico Casino Hotels ; 2. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Excite. Swirls of Cash. Upcoming Events. at Isleta Resort & Casino. Saturdays in. It's a warm, friendly environment with slot machines. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. 1. Colorful bingo cards and round bingo balls w/numbers.