. Our New Mexico casino is open 24/7 daily. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. The Travel center includes a casino area with 45 slot machines. Sky City Casino is open 24 hours daily. Learn More. Unwind. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. at Isleta Resort & Casino. Seadust Cancun Family Resort · 6, reviews. Swirls of Cash. #1 Best Value of 24 Mexico Casino Hotels ; 2. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Must be 21+. These casinos and gaming sites are owned by 14 New Mexico. 1. Win. Saturdays in. It's a warm, friendly environment with slot machines. Indulge. The Pyramid Cancun · 4, reviews. Excite. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Open 24 hours, 7 days a week! What's happening. Upcoming Events. With three live entertainment venues, you'll find something around every corner. No Smoking Facility. A warm and friendly environment with slot machines at the Main Casino. Colorful bingo cards and round bingo balls w/numbers. #2 Best Value of 24 Mexico. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties.